Syphilis transmission predominantly occurs through sexual contact, including vaginal, anal, and oral sex. Additionally, the infection can spread through direct contact with syphilis sores, which may appear on the genitals, rectum, or mouth. Moreover, there is a risk of syphilis transmission from an infected mother to her unborn child during pregnancy or childbirth, leading to congenital syphilis. Prioritizing safe sex practices, such as using condoms or dental dams during sexual activity, is crucial to mitigating syphilis transmission. Regular testing and early treatment play pivotal roles in preventing complications and reducing the risk of syphilis transmission.